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Analyst
Casey Woodring
Period: Reporting periods mapped to calendar 2024 Q3 – 2026 Q3 (9 quarters).
- Questions
- 44on tracked calls
- Challenge rate
- 2%1 of 44 questions
- Companies
- 9questioned at least once
- Reporting periods
- 9with questions
These figures cover the whole profile: every tracked question, all reporting periods.
How to read these numbers
Challenge rate is the share of questions that pushed back, pressed for specifics or questioned management’s assumptions. It describes how questions were asked on the calls tracked here; it does not measure whether any view turned out to be right.
Rounding. Rates are rounded to whole percentages, so a small share can show as 0% even when some questions were challenging. The count beside each rate is exact; “none of N questions” means no question was challenging.
No questions recorded. “—” means there is nothing to calculate: no questions were recorded for that period on the calls tracked here. It does not mean there was no activity.
Fewer than 3 questions. A company-level rate is withheld when fewer than 3 questions were recorded for that company; the questions are still counted everywhere else.
Small samples. Profiles with fewer than 10 questions are marked Limited sample.
Reporting periods. Questions are grouped by the calendar quarter each company’s fiscal reporting period maps to, not by the date of the call. Periods without a calendar mapping are listed separately under their fiscal label.
Questions asked
Grouped by company, most questions first. Open a company to read its questions, newest reporting period first.
Showing 44 of 44 questions from 9 companies
CRLCharles River Laboratories8 questions · 6 reporting periods · 0 of 8 challenging
Calendar 2026 Q2
how much your win rate has maybe increased as a result of more of this in-sourcing
Show response
Girshick declined to quantify market share but pointed to an uptick in capture rate and NHP supply security as a growing competitive differentiator.
You mentioned academic and government is still weak. We've heard sort of mixed signals from some of the tools vendors
Show response
Girshick said academic and government demand (about 10% of the company) is stable but not growing on flat NIH budgets and grant uncertainty; CRADL is also stable, held back by slow new-company formation.
Calendar 2025 Q4
you talked about maintaining dry powder for M&A. How should we think about that in relation to some of the comments
Show response
Jim said NHP sourcing is secured via NovoPrim and KF with no further acquisitions needed. Balance sheet strong at high-two-times leverage. M&A focus on bioanalysis and potentially China. Buybacks dependent on alternative uses and share price.
Calendar 2025 Q3
Can you just elaborate on that and if that's expected to be a drag on DSA margins next year?
Show response
Knell explained higher NHP costs are due to needing third-party sourcing to meet demand that exceeded initial plans; not expected to continue in 2026 if demand levels can be planned for consistently.
Calendar 2025 Q2
on the forward outlook, how should we think about potential headwinds here for large pharma demand?
Show response
Foster said guidance accommodates rougher conditions; minimal impact from tariffs, drug pricing, or NIH cuts so far. Any material impact more likely in 2026 than remainder of 2025.
Can you just elaborate on what's driving that? What sort of margin differential in the work that's getting canceled looks like?
Show response
Foster said no significant margin difference between canceled work and other studies; cancellations reflect client portfolio prioritization and what they have ready, not a concerning trend. Does not expect it to continue.
Calendar 2025 Q1
what your updated expectations are for biotech and DSA this year, just given the weaker funding numbers to start the year?
Show response
Pease said tariffs have not impacted pharma R&D dollars; direct tariff impact to CRL is very modest. Foster said biotech funding situation is not improving so no dramatic demand change expected but quality-focused clients will continue using CRL.
Calendar 2024 Q4
any quick thoughts on how something like that would impact pharma budgets and that customer group's preclinical drug development spending
Show response
James acknowledged tariffs could support US drug development but declined to speculate. Said clients are not yet sharing concerns about RFK or tariff impacts.
HOLXHologic8 questions · 4 reporting periods · 1 of 8 challenging
Calendar 2025 Q2
You mentioned 3D gantry placements grew sequentially, but imaging revenue declined sequentially. So just maybe some more color there.
Show response
Karleen clarified 3D gantry line was up sequentially while other imaging components declined. Expects another sequential uptick in Q4 gantry shipments with better visibility than Q3.
at what point you'll run into the law of large numbers there. And ultimately, where do you think diagnostics growth will shake out relative to that mid-single-digit range
Show response
Karleen expects diagnostics within mid-single-digit range for FY2026, with H1 headwinds from China and HIV pressuring growth. BV/CV has lots of runway. Steve highlighted Fusion menu expansion and Genius digital cytology as additional growth layers.
Calendar 2025 Q1
it's pretty insulated from a lot of this macro noise. So curious how that's contributing to that molecular growth rate moving forward?
Show response
Karleen noted Biotheranostics is accretive to molecular growth but Q2 benefited from cash-basis revenue lumpiness and a lighter prior-year comp, so growth rate may moderate.
I'm just curious on that 12% non-product revenue growth rate, you called out mainly on the breast service component. How did that compare to your expectations in the quarter?
Show response
Karleen attributed strong service growth to improved attach rates, optimized pricing, and growing installed base, performing in line with expectations.
Calendar 2024 Q4
can you break out performance in the quarter between US and international customers?
Show response
Karleen confirmed mid-single-digit declines in both US and international Breast Health, with international slightly worse due to budget constraints.
the potential margin benefit once the consolidation is finished and the next gantry is launched and ramped?
Show response
Karleen noted facility savings and higher ASP on new gantry offset by higher component costs, resulting in roughly neutral margin profile.
Calendar 2024 Q3
if there's anything baked in there from a supply chain perspective that 19.5% tax rate for '25
Show response
Karleen noted 19.5% already represents a 25bps reduction from FY24 via reducing non-deductible foreign losses. Not ready to commit lower.
I was curious if you could break out the 1Q guide by business segment
Show response
Karleen gave directional guidance only: diagnostics mid-single-digit growth, other segments below. Essex confirmed international expected to grow faster than domestic.
MTDMettler Toledo6 questions · 4 reporting periods · 0 of 6 challenging
Calendar 2026 Q2
curious just how reshoring conversations have trended, if those have picked up at all?
Show response
Patrick pointed to RFQ activity but characterized larger factory investments as still early innings, so no firm near-term order commitment.
Calendar 2026 Q1
Is the March change in Harmonized Tariff Schedule codes included in that?
Show response
Shawn described two dynamics: a lower-rate tariff benefit assumed to revert midyear, offset by inflationary pressures with mitigation upside.
Calendar 2025 Q3
Just what's the latest there on the ground in terms of potential stimulus and what that could mean for 2026
Show response
Shawn noted current stimulus program not very relevant to MTD portfolio and customer base. Broader fiscal stimulus packages would benefit more as in past. Teams highly agile and effective in dynamic China market.
the sort of strategy shift towards focusing on the midrange market there that's really driving growth. So just curious if that's a tailwind that you're assuming extends into 2026
Show response
Shawn confirmed product introduction cadence continuing into 2026 providing confidence in sustained PI momentum. Some synergy opportunities with acquisitions including new service capabilities not previously offered.
Calendar 2025 Q2
just curious on timing of when you would expect some of these CapEx announcements to eventually flow through into orders and revenue for you guys
Show response
Patrick said 2026 is when onshoring benefits start with more momentum in following years. Currently in discussion phase with customers about portfolio capabilities.
maybe just parse out drivers by segment and the outlook in that region for the back half of the year
Show response
Shawn explained Europe shortfall was lab (flattish vs expected growth) due to uncertainty. Industrial up slightly. Full year flattish, up low single digit ex-shipping delays.
AAgilent Technologies5 questions · 4 reporting periods · 0 of 5 challenging
Calendar 2026 Q3
So diagnostics grew 6% this quarter. You noted it was a little bit below your expectations.
Show response
Simon attributed the diagnostics shortfall to backlog timing while noting strong order entry, double-digit pathology growth, and Omnis adoption.
Calendar 2026 Q2
would be curious to hear how much that forensic TSA 1-timer you called out was in the quarter. Was that baked into the guide
Show response
Management quantified $5M of $9M TSA contract recognized in Q2 and highlighted strong positioning for larger aviation security tenders. Chemical CapEx strength confirmed across all regions, not limited to US.
Calendar 2026 Q1
Can you maybe just elaborate on what the financial impact could look like from those contracts
Show response
Padraig described enterprise services as flywheel: higher consumables and services attach, early warning on replacement cycles. Angelica elaborated on embedding service experts, competitive displacement visibility, and compounding growth insights.
Can you just talk about what LC/MS grew in the quarter and walk through the growth phasing for LC and LC/MS over the course of the year?
Show response
Simon confirmed LC high single digits with particular strength in China/APAC. Infinity III still early-to-mid replacement cycle. LC/MS in line with expectations off tough compare. Pro iQ 40% growth with notable share gains per industry data.
Calendar 2025 Q4
within pharma in the quarter, excluding the CDMO, could you break down large molecule versus small molecule growth?
Show response
Padraig confirmed roughly 50/50 split with both large and small molecule growing about 10%. Expected to continue into FY2026. Direct but brief.
DHRDanaher Corporation4 questions · 2 reporting periods · 0 of 4 challenging
Calendar 2026 Q2
The consumables order growth of mid-teens, does that include the pushed out revenue here?
Show response
Rainer clarified the pushed orders were in backlog, not book-and-turn, and reaffirmed broad-based mid-teens order growth; direct.
can you just elaborate on updated expectations for Radiometer and Leica
Show response
Rainer said Radiometer and Leica Biosystems keep growing high single digits, aided by StatLab; direct.
Calendar 2026 Q1
maybe can you just walk through what exactly is offsetting that lower respiratory number for the year?
Show response
Blair cited Cepheid share gains in core molecular (GI panel, MVP panel performing well), Beckman Coulter mid-single-digit ex-China growth with new DxI 9000 placements, and China VBP headwinds tracking to the $75-$100M full-year assumption with better patient volumes.
can you just give us any sense of what orders grew sequentially in 4Q or what book-to-bill was in the quarter?
Show response
Blair acknowledged Q1 orders were down sequentially (normal seasonality) but emphasized the YoY inflection as the key marker. Described two vectors driving equipment orders: underinvestment-driven capacity expansion and reshoring dynamics. Did not provide book-to-bill.
TEMTempus AI, Inc.4 questions · 4 reporting periods · 0 of 4 challenging
Calendar 2026 Q1
walk us through how you see EBITDA progressing over the course of the year and the cadence of gross margins
Show response
Jim said EBITDA phases up through the year, back-half weighted by higher-margin data.
Calendar 2025 Q4
Can you walk us through what the guide embeds for data and services revenue in 2026?
Show response
Eric said 2026 data visibility is the strongest ever given $1.1 billion-plus of backlog.
Calendar 2025 Q3
just wondering if you're seeing a similar pickup in xF and more of a marketed shift towards liquid?
Show response
Eric saw strong growth in both solid and liquid but no fundamental shift from solid to liquid.
Calendar 2024 Q4
it looks like Ambry is now an implied 17% top line growth rate if keeping core Tempus at 30%
Show response
Eric confirmed the split, framing Ambry high-teens against 2024 accelerants and core Tempus near 30%.
Show 3 more companies
TMOThermo Fisher Scientific4 questions · 2 reporting periods · 0 of 4 challenging
Calendar 2026 Q1
curious if you'd expect China to return to growth at any point this year?
Show response
Marc said China had low single-digit decline with muted A&G but strong pharma/biotech. Left China incrementally more positive after March visit but not assuming meaningful growth this year.
maybe just walk through where the softness occurred in the quarter. I think we've seen a couple of reports of a weaker microbiology market in China
Show response
Marc attributed Specialty Diagnostics decline to selling day impact on consumables and tough respiratory comps, with phasing expected to improve through the year.
Calendar 2025 Q4
Curious on how the performance played out relative to your expectations in the quarter
Show response
Casper said instruments were flat in Q4 against a tougher comp, with pharma and biotech performing well while academic/government and China faced headwinds.
what's assumed for US academic and government growth in 2026
Show response
Casper assumed similar cautious academic conditions for 2026, expecting flat to slightly up NIH budget to create tailwinds over the next couple of years.
ILMNIllumina, Inc.3 questions · 3 reporting periods · 0 of 3 challenging
Calendar 2026 Q2
Could you walk us through how low and mid throughput instruments performed in the quarter?
Show response
Answering via Jaden on for Casey, Jacob said low throughput (MiSeq i100) is very strong while mid throughput stays muted on the macro environment but should recover mid-term.
Calendar 2026 Q1
Did you quantify the headwind from inflationary pressure on things like memory chips and freight
Show response
Ankur said the inflation is within an actionable range and expects full-year X placements reasonably above the initial range, with Q2 near Q1 levels.
Calendar 2025 Q4
walk us through how conversations are going there and the range of outcomes.
Show response
Jacob said Illumina remains on the UAL but sees good line of sight to 2026 China (<5% of business) and upside if delisted; Ankur outlined a multi-year BioInsight subscription and data monetization.
WATWaters Corporation2 questions · 2 reporting periods · 0 of 2 challenging
Calendar 2025 Q4
Curious if you could just unpack that for us. How much of that was price? How much was new product contribution in bioseparations
Show response
CFO confirmed 400-450bps like-for-like chemistry pricing and 200bps overall portfolio pricing, running ahead of Investor Day commitments. BD pricing historically 40-50bps presents significant opportunity.
Calendar 2025 Q3
TA. You said that business came back faster than expected. I think you had previously assumed TA would be down 5% in the second half
Show response
CFO attributed TA recovery to tariff uncertainty stabilizing, with improving interest rate outlook opening previously stranded projects.
Challenge rate by company
Every company this analyst questioned, most questions first. A company-level rate is shown from 3 questions; below that it is withheld.
| Company | Questions | Challenge rate |
|---|---|---|
| CRL Charles River Laboratories | 8 | 0%none of 8 questions |
| HOLX Hologic | 8 | 13%1 of 8 questions |
| MTD Mettler Toledo | 6 | 0%none of 6 questions |
| A Agilent Technologies | 5 | 0%none of 5 questions |
| DHR Danaher Corporation | 4 | 0%none of 4 questions |
| TEM Tempus AI, Inc. | 4 | 0%none of 4 questions |
| TMO Thermo Fisher Scientific | 4 | 0%none of 4 questions |
| ILMN Illumina, Inc. | 3 | 0%none of 3 questions |
| WAT Waters Corporation | 2 | —Rate withheld: fewer than 3 questions |
- CRLCharles River Laboratories · 8 questions0%none of 8 questions
- HOLXHologic · 8 questions13%1 of 8 questions
- MTDMettler Toledo · 6 questions0%none of 6 questions
- AAgilent Technologies · 5 questions0%none of 5 questions
- DHRDanaher Corporation · 4 questions0%none of 4 questions
- TEMTempus AI, Inc. · 4 questions0%none of 4 questions
- TMOThermo Fisher Scientific · 4 questions0%none of 4 questions
- ILMNIllumina, Inc. · 3 questions0%none of 3 questions
- WATWaters Corporation · 2 questions—rate withheld: under 3 questions
Activity by reporting period
Questions recorded for each calendar quarter that companies’ reporting periods map to (not the call date), with the challenge rate for that period. Periods inside the range with no questions are shown as “No questions recorded”.
| Calendar period | Questions | Challenge rate | Companies |
|---|---|---|---|
| 2024 Q3 | 2 | 0%none of 2 questions | 1 |
| 2024 Q4 | 4 | 0%none of 4 questions | 3 |
| 2025 Q1 | 3 | 0%none of 3 questions | 2 |
| 2025 Q2 | 6 | 17%1 of 6 questions | 3 |
| 2025 Q3 | 5 | 0%none of 5 questions | 4 |
| 2025 Q4 | 7 | 0%none of 7 questions | 6 |
| 2026 Q1 | 9 | 0%none of 9 questions | 6 |
| 2026 Q2 | 7 | 0%none of 7 questions | 5 |
| 2026 Q3 | 1 | 0%none of 1 question | 1 |
- 2024 Q32 questions · challenge rate 0% (none of 2 questions) · 1 company
- 2024 Q44 questions · challenge rate 0% (none of 4 questions) · 3 companies
- 2025 Q13 questions · challenge rate 0% (none of 3 questions) · 2 companies
- 2025 Q26 questions · challenge rate 17% (1 of 6 questions) · 3 companies
- 2025 Q35 questions · challenge rate 0% (none of 5 questions) · 4 companies
- 2025 Q47 questions · challenge rate 0% (none of 7 questions) · 6 companies
- 2026 Q19 questions · challenge rate 0% (none of 9 questions) · 6 companies
- 2026 Q27 questions · challenge rate 0% (none of 7 questions) · 5 companies
- 2026 Q31 question · challenge rate 0% (none of 1 question) · 1 company
Topics
Topics tagged on this analyst’s questions.
- Demand22
- Revenue Growth19
- Geographic Expansion7
- Competitive Dynamics6
- Margin6
- Regulation Policy5
- Capex Investment4
- Trade Tariffs4
- Macroeconomic3
- Cost Pressure3
Show all 18 topics
- Guidance Reliability3
- Supply Chain2
- Product Launch2
- Innovation & R&D2
- Capital Allocation1
- M&A1
- Pricing1
- Credit1