Start 30 days free, no card. Full Pro access for a month, then decide. Start free
Analyst
Doug Schenkel
Period: Reporting periods mapped to calendar 2024 Q4 – 2026 Q1 (6 quarters).
- Questions
- 52on tracked calls
- Challenge rate
- 19%10 of 52 questions
- Companies
- 10questioned at least once
- Reporting periods
- 6with questions
These figures cover the whole profile: every tracked question, all reporting periods.
How to read these numbers
Challenge rate is the share of questions that pushed back, pressed for specifics or questioned management’s assumptions. It describes how questions were asked on the calls tracked here; it does not measure whether any view turned out to be right.
Rounding. Rates are rounded to whole percentages, so a small share can show as 0% even when some questions were challenging. The count beside each rate is exact; “none of N questions” means no question was challenging.
No questions recorded. “—” means there is nothing to calculate: no questions were recorded for that period on the calls tracked here. It does not mean there was no activity.
Fewer than 3 questions. A company-level rate is withheld when fewer than 3 questions were recorded for that company; the questions are still counted everywhere else.
Small samples. Profiles with fewer than 10 questions are marked Limited sample.
Reporting periods. Questions are grouped by the calendar quarter each company’s fiscal reporting period maps to, not by the date of the call. Periods without a calendar mapping are listed separately under their fiscal label.
Questions asked
Grouped by company, most questions first. Open a company to read its questions, newest reporting period first.
Showing 52 of 52 questions from 10 companies
DHRDanaher Corporation10 questions · 6 reporting periods · 2 of 10 challenging
Calendar 2026 Q1
from a readiness standpoint, could you do something in any segment as we sit here today
Show response
Blair confirmed M&A readiness across all 3 segments with no segment-level constraints from the pending Masimo integration. Signaled both financial capacity and management bandwidth are available.
What gets you to the high end of guidance for the year? Is it really just what you described there
Show response
Gugino outlined 3 requirements for high-end attainment: further Life Sciences end market improvement, bioprocessing acceleration beyond high single digits in consumables plus equipment growth, and above-normal Q4 respiratory season back to ~$1.8B endemic rate.
Calendar 2025 Q4
Can you just describe the M&A environment and your readiness and your priorities to potentially get a little more aggressive
Show response
Rainer confirmed improving M&A environment with better valuations and moderating interest rates. Balance sheet is prime for action. Maintaining disciplined framework but bias toward M&A remains strong.
it's a smidge surprising you didn't guide for maybe a little more growth at that line. Was there any pull forward of demand
Show response
Matt emphasized prudence, one quarter of growth is not a trend. Guiding flat for equipment as starting point. Will adjust as more data points confirm the trajectory.
Calendar 2025 Q3
Have you seen any change in activity over the last few weeks or even just -- even in the tone of discussions
Show response
Rainer confirmed improving tone in pharma discussions but not yet reflected in guidance, needs demonstrated order patterns before calling the trend. More confidence on tariffs and MFN becoming plannable.
is there an argument that even though you talked about 100 basis points of margin expansion potential next year
Show response
Matt confirmed north of 100bps expansion is the right frame. $250M net savings drives $0.30 EPS tailwind. Company wants room to continue investing while delivering high-single-digit EPS growth.
Calendar 2025 Q2
you had previously told us to expect high single-digit bioprocessing revenue growth for the year. Is that still the case
Show response
Confirmed high-single-digit guide. H1 pricing 1.5-2%, similar or slightly better in H2. D&M slightly lower offset by better bioprocessing; full segment guide maintained.
Calendar 2025 Q1
I just want to make sure this is a continuation of trend and not really anything new in terms of a further deterioration
Show response
Aldevron tracking as anticipated, expects improvement in H2 as comps ease. On EPS, $7.60-$7.75 includes cushion from remaining ~$100M of cost savings not yet in guide, balancing macro uncertainty.
Calendar 2024 Q4
So it's hard for a stock to work, when the estimates keep moving in the wrong direction
Show response
Matt acknowledged EPS trajectory concern but defended bottom-up approach. Noted external headwinds were worked through and margin profile remained strong despite two down years.
this implies kind of what's embedded into your guidance, is an implied 5% core and normalized diagnostic growth rate
Show response
Matt confirmed diagnostics ex-China is mid-to-high single-digits, in line with long-term aspiration. Headwinds are China VBP and respiratory normalization.
AAgilent Technologies9 questions · 5 reporting periods · 2 of 9 challenging
Calendar 2026 Q1
how would you describe demand month-by-month going back to, say, November and December and through the beginning of the calendar year?
Show response
Padraig described steady to growing funnels. Reasonable budget flush in December, some intra-quarter disruption in Europe and weather in January. No deterioration in CapEx conditions. MFN deals reducing tariff uncertainty for pharma. Comprehensive.
how would you describe the environment, your readiness and your appetite to do a multibillion dollar deal?
Show response
Adam was deliberate: no arbitrary size filter but very high bar for transformative deals. Organic business is strong enough without transformation. Focused on strategic fit, right to win, integrability, and right price. Nice opportunities being evaluated.
Calendar 2025 Q4
I think you guys were down 10% constant currency in the quarter, if I updated the model right. You know, I think this is a little bit surprising given seasonality
Show response
Padraig attributed to US federal spending reductions. Americas instruments down mid-twenties, services/consumables resilient at low single digits. Ex US stable sequentially. No material government shutdown impact. Continued FY2026 softness expected. Direct.
How big is this business? I'm thinking it's probably around $100 million coming out of last year.
Show response
Padraig quantified GLP-1 at ~$130M for FY2025, split evenly BioVectra/analytical lab. Q4 revenue ~$40M (60% BioVectra, 40% analytical). Analytical lab grew 40% on Alturo columns and Infinity 3. India as key generics opportunity. Very detailed.
Calendar 2025 Q3
How do you balance momentum and strength with the goal of maybe skewing the error bars around your guidance targets to the upside?
Show response
Padraig stated very good Q4 visibility on orders, revenue, and margins. Positive momentum expected to continue into FY2026 but formal guidance deferred to next quarter. Direct.
how would you describe organizational readiness for something bigger given how how how many changes have occurred in leadership over the past year?
Show response
Padraig emphasized Ignite as integration capability, M&A expected to be more meaningful going forward. Disciplined approach aligned to strategy pillars. Small list of high-quality targets. Also investing heavily in digital/CRM internally.
Calendar 2025 Q1
it would be interesting to hear if there's anything, interesting that occurred in terms of a particular rebound in specific instrument categories, specific geographies
Show response
Padraig confirmed solid December driven by Infinity III, PFAS, GLP-1. January steady with only academia softness. PFAS business unchanged. Thorough.
Calendar 2024 Q4
is it fair to say that the error bar around your assumptions are wider than normal heading into a new fiscal year and your intent across the board was to make assumptions
Show response
Padraig openly confirmed wider error bars and intentional conservatism across China, LC replacement, and policy uncertainty. Transparent.
I believe in your prepared remarks, you indicated that small molecule was up low single digits while biopharma was down mid-singles. If I have that right, is that comp effect
Show response
Bob explained NASD impact on biopharma numbers, volume dynamics in small molecule, and why it was first to recover. Detailed and analytical.
ILMNIllumina, Inc.6 questions · 6 reporting periods · 1 of 6 challenging
Calendar 2026 Q1
How should we think about the margin progression throughout the year?
Show response
Ankur (answering Madeleine on for Doug) cited higher instrument mix, inflation and a full quarter of SomaLogic pressuring Q2, with mitigation benefits visible in H2.
Calendar 2025 Q4
Does guidance embed an assumption that you essentially end the year at 26% to 27% operating margin?
Show response
Jacob reaffirmed the 2027 26% margin target and to get as close as possible including SomaLogic; Ankur confirmed the Q4 exit rate typically runs above the full-year 24.5%.
Calendar 2025 Q3
mathematically, it gets me to low single-digit revenue growth, at least as a starting point for next year.
Show response
Jacob broadly endorsed the clinical-led framework without guiding, excluding China; Ankur pointed to further margin expansion from cost actions and operating leverage.
Calendar 2025 Q2
your guidance implies the company will generate about 2 points of revenue growth in the fourth quarter, excluding China
Show response
Jacob declined to give 2026 guidance but confirmed the X transition and clinical as the main drivers, with multiomics adding growth from 2026-2027.
Calendar 2025 Q1
outside of China, what was your total clinical revenue growth and what was your total research growth
Show response
Ankur quantified clinical consumables up mid-single digits and research down mid-to-high single digits, guiding research to a ~15% decline for the rest of the year.
Calendar 2024 Q4
I'm wondering if you would at least be willing to talk about the levers you have identified
Show response
Ankur pointed to 170bps of margin expansion in the base case plus additional earnings-growth opportunities, without ring-fencing China.
MTDMettler Toledo6 questions · 4 reporting periods · 0 of 6 challenging
Calendar 2026 Q1
Could you elaborate a bit more on the grant proceeds recognized in the quarter?
Show response
Shawn described a local Shanghai government grant encouraging capacity and research, split between CapEx and OpEx, excluded from free cash flow.
any product categories or geographies that got, you know, notably better or worse in April versus March
Show response
Shawn declined month-level detail, pointing back to the Q2 and full-year guidance by product area and region.
Calendar 2025 Q4
What would you call out as driving the underlying improvement? So not just in process analytics and bioprocessing, but more broadly
Show response
Patrick confirmed some budget flush activity with better momentum late in Q4. Beyond bioprocessing, LabX software solution driving automation of broader workflows in R&D and QA/QC labs. Digital capabilities and connectivity across lab portfolio creating competitive differentiation.
Calendar 2025 Q3
how much of this was driven by PA process analytics versus traditional lab equipment
Show response
Shawn confirmed PA/bioprocessing was lab highlight plus power grid investments for data centers. Analytical instruments and weighing also grew well. Liquid handling soft spot. On industrial, transportation/logistics dynamic dimensioning contributed, timing skewed Q3 vs Q4. Q4 core industrial guided low single digit.
Calendar 2025 Q2
You talked in your prepared remarks about strong demand for automation. I'm just wondering if you could tell us a little bit more about that
Show response
Patrick highlighted automation solution providers calling on MTD innovations across pharma, general manufacturing. Good momentum in US, China, and Asia Pacific.
if Europe kind of returns to normal and starts to get a little bit better, and by normal, I mean, what you've seen in the last few quarters, if China starts to get a smidge better
Show response
Shawn acknowledged Europe upside potential offset by tougher Q4 comps. China remains wildcard, bouncing along bottom. Well positioned with China-for-China business but cautious H2 guide.
RVTYRevvity5 questions · 3 reporting periods · 0 of 5 challenging
Calendar 2025 Q3
I believe China Diagnostics is down to about 5% of total sales exiting Q3. I want to make sure that's right
Show response
Max corrected China DX to ~6% of revenue. Expects DRG headwinds to continue until Q2 2026 anniversary, then low-single-digit growth per LRP. IDx ex-China up high single digits.
Calendar 2025 Q2
When would you expect this to annualize? Do you have visibility on whether or not this is the last cut?
Show response
Prahlad noted annualization expected around late April 2026. IDx China now less than 6% of revenue, likely less than 5% in FY26.
it looks like you're assuming similar revenue pacing to last year. I just want to make sure that's right
Show response
Max confirmed normal Q3-to-Q4 seasonality with Genomics England ramp and larger Signals quarter in Q4.
Calendar 2024 Q4
What does your guidance assume for core growth within the region this year? How are you thinking about stimulus within the context of guidance?
Show response
Max confirmed China assumed in line with company at 3-5%, LS at higher end, Diagnostics at lower. Stimulus modest.
what are the major areas where you would say things are back to normal, where are the things were -- or areas where you would say we're getting close?
Show response
Prahlad provided clear breakdown: Diagnostics and software at normal, reagents getting closer, instruments still lagging.
WSTWest Pharmaceutical Services5 questions · 5 reporting periods · 1 of 5 challenging
Calendar 2025 Q4
Are you comfortable saying, as built, even in a conservative scenario for GLP-1s, that your revenue can grow at least mid to high single digits over the next several years
Show response
Bob confirmed comfort with mid-to-high single digit revenue growth over the next several years, combining conservative GLP-1 assumptions with non-GLP-1 HVP recovery and Annex-1 tailwinds.
Calendar 2025 Q3
I want to confirm that you essentially bumped up guidance by the magnitude of the revenue beat
Show response
Bob confirmed no material pull-forward in Q3, noting Q4 is actually an acceleration on a 2-year stack. On visibility, emphasized improving transparency, deeper segment accountability, and closer customer engagement as reducing risk profile.
Calendar 2025 Q2
as currently built and with no material changes in policy dynamics are there any things you would want us to contemplate as we update our out-year model
Show response
Bernard confirmed tariff guidance based on known rates at time of guidance, with Japan change not fully contemplated but immaterial. Eric expressed strong confidence in HVP momentum building but declined to comment specifically on 2026.
Calendar 2025 Q1
could you share anything in terms of what are the what's the status of discussions pursuant to getting the price
Show response
Bernard confirmed no SmartDose pricing or tariff pass-through embedded in guidance; both represent potential upside if materialized.
Calendar 2024 Q4
GLP-1 is a percentage of sales are about 10%. I just want to make sure that's right
Show response
Eric confirmed GLP-1 is approximately 10% of total revenue, split roughly 40% of contract manufacturing and mid-single digits of proprietary.
Show 4 more companies
WATWaters Corporation4 questions · 3 reporting periods · 3 of 4 challenging
Calendar 2026 Q1
I'm just wondering if there's been any notable competitive responses worth calling out
Show response
Doug asked about competitive response to Waters' new discipline and PE-owned competitor dynamics. Udit emphasized leading brands across all four divisions and expected rational pricing from PE players. Confident but no specific competitive data points.
Calendar 2025 Q4
your initial year 1 guidance assumes you cut 5% to 6% of the acquired businesses OpEx, assuming I have that math right
Show response
CFO noted underwriting assumed 4-4.5% vs 6% typical for deals this size and 8% achieved at MilliporeSigma. Kept room for integration skeletons while confirming on track for deal announcement commitments.
Calendar 2025 Q3
you beat the quarter from a revenue standpoint, but you increased full year guidance by less than the magnitude of the beat
Show response
CFO noted quarterly timing of bonus true-ups, commissions and discrete tax items but stressed full-year delivery is on track.
The downside to that is the comps are difficult. I just want to make sure, as we sit here today, are you still comfortable with us modeling something like 6% to 8% core growth
Show response
Management described excellent 2026 setup with replacement cycle mid-innings, multiple new product catalysts and improving end markets.
TMOThermo Fisher Scientific3 questions · 2 reporting periods · 1 of 3 challenging
Calendar 2025 Q1
you have to at least contemplate a scenario where the market growth rate is structurally lower
Show response
Casper acknowledged GDP growth is a factor in long-term market growth but emphasized industry resilience and committed to transparent communication if views change.
I'm curious what you're seeing in terms of movement towards reshoring in the US
Show response
Casper said new facility announcements drive meaningful revenue across bioproduction and bioscience, but timing is mainly 2026 and beyond.
Calendar 2024 Q4
are you expecting to exit 2025 back in your targeted 7% to 9% organic growth range
Show response
Casper indicated the exit rate would be strong mid-single digits (not yet 7-9% due to pandemic headwind) and attributed margin expansion to PPI execution, not mix.
HOLXHologic2 questions · 2 reporting periods · 0 of 2 challenging
Calendar 2025 Q2
Are there any dynamics we should be contemplating in our models, either tailwinds or headwinds that could move you off trend towards continued progress
Show response
Karleen flagged Fluoroscan discontinuation and continuing China/HIV headwinds into FY2026 H1 as key modeling considerations. Also confirmed mid-single-digit organic growth expectation for FY2026.
Calendar 2024 Q4
how much of the change in your assumption that you've embedded into guidance for Breast Health as a function of market conditions
Show response
Steve weighted market conditions as bigger driver than pre-launch stalling. Karleen outlined M&A criteria: revenue accretive, at or above corporate gross margins, double-digit ROIC within reasonable timeframe.
TEMTempus AI, Inc.2 questions · 2 reporting periods · 0 of 2 challenging
Calendar 2025 Q2
Is there a good rule of thumb on just how you're going to think about partnering versus organic?
Show response
Eric said any deal must be synergistic and not derail the path to adjusted EBITDA positive.
Calendar 2024 Q4
what's the appetite for more M&A based on your balance sheet situation in the current market environment?
Show response
Eric said nothing big is on the horizon; only smaller data/AI deals are likely.
Challenge rate by company
Every company this analyst questioned, most questions first. A company-level rate is shown from 3 questions; below that it is withheld.
| Company | Questions | Challenge rate |
|---|---|---|
| DHR Danaher Corporation | 10 | 20%2 of 10 questions |
| A Agilent Technologies | 9 | 22%2 of 9 questions |
| ILMN Illumina, Inc. | 6 | 17%1 of 6 questions |
| MTD Mettler Toledo | 6 | 0%none of 6 questions |
| RVTY Revvity | 5 | 0%none of 5 questions |
| WST West Pharmaceutical Services | 5 | 20%1 of 5 questions |
| WAT Waters Corporation | 4 | 75%3 of 4 questions |
| TMO Thermo Fisher Scientific | 3 | 33%1 of 3 questions |
| HOLX Hologic | 2 | —Rate withheld: fewer than 3 questions |
| TEM Tempus AI, Inc. | 2 | —Rate withheld: fewer than 3 questions |
- DHRDanaher Corporation · 10 questions20%2 of 10 questions
- AAgilent Technologies · 9 questions22%2 of 9 questions
- ILMNIllumina, Inc. · 6 questions17%1 of 6 questions
- MTDMettler Toledo · 6 questions0%none of 6 questions
- RVTYRevvity · 5 questions0%none of 5 questions
- WSTWest Pharmaceutical Services · 5 questions20%1 of 5 questions
- WATWaters Corporation · 4 questions75%3 of 4 questions
- TMOThermo Fisher Scientific · 3 questions33%1 of 3 questions
- HOLXHologic · 2 questions—rate withheld: under 3 questions
- TEMTempus AI, Inc. · 2 questions—rate withheld: under 3 questions
Activity by reporting period
Questions recorded for each calendar quarter that companies’ reporting periods map to (not the call date), with the challenge rate for that period. Periods inside the range with no questions are shown as “No questions recorded”.
| Calendar period | Questions | Challenge rate | Companies |
|---|---|---|---|
| 2024 Q4 | 11 | 27%3 of 11 questions | 8 |
| 2025 Q1 | 6 | 17%1 of 6 questions | 5 |
| 2025 Q2 | 9 | 0%none of 9 questions | 7 |
| 2025 Q3 | 10 | 30%3 of 10 questions | 7 |
| 2025 Q4 | 8 | 38%3 of 8 questions | 6 |
| 2026 Q1 | 8 | 0%none of 8 questions | 5 |
- 2024 Q411 questions · challenge rate 27% (3 of 11 questions) · 8 companies
- 2025 Q16 questions · challenge rate 17% (1 of 6 questions) · 5 companies
- 2025 Q29 questions · challenge rate 0% (none of 9 questions) · 7 companies
- 2025 Q310 questions · challenge rate 30% (3 of 10 questions) · 7 companies
- 2025 Q48 questions · challenge rate 38% (3 of 8 questions) · 6 companies
- 2026 Q18 questions · challenge rate 0% (none of 8 questions) · 5 companies
Topics
Topics tagged on this analyst’s questions.
- Guidance Reliability18
- Revenue Growth17
- Demand16
- M&A10
- Capital Allocation8
- Margin7
- Macroeconomic6
- Regulation Policy5
- Geographic Expansion4
- Capex Investment4
Show all 15 topics
- Competitive Dynamics4
- Pricing2
- Trade Tariffs2
- Cost Pressure1
- Innovation & R&D1