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Analyst

Doug Schenkel

Wolfe Research · covers Healthcare

Period: Reporting periods mapped to calendar 2024 Q4 – 2026 Q1 (6 quarters).

Questions
52on tracked calls
Challenge rate
19%10 of 52 questions
Companies
10questioned at least once
Reporting periods
6with questions

These figures cover the whole profile: every tracked question, all reporting periods.

How to read these numbers

Challenge rate is the share of questions that pushed back, pressed for specifics or questioned management’s assumptions. It describes how questions were asked on the calls tracked here; it does not measure whether any view turned out to be right.

Rounding. Rates are rounded to whole percentages, so a small share can show as 0% even when some questions were challenging. The count beside each rate is exact; “none of N questions” means no question was challenging.

No questions recorded. “—” means there is nothing to calculate: no questions were recorded for that period on the calls tracked here. It does not mean there was no activity.

Fewer than 3 questions. A company-level rate is withheld when fewer than 3 questions were recorded for that company; the questions are still counted everywhere else.

Small samples. Profiles with fewer than 10 questions are marked Limited sample.

Reporting periods. Questions are grouped by the calendar quarter each company’s fiscal reporting period maps to, not by the date of the call. Periods without a calendar mapping are listed separately under their fiscal label.

Questions asked

Grouped by company, most questions first. Open a company to read its questions, newest reporting period first.

Showing 52 of 52 questions from 10 companies

DHRDanaher Corporation10 questions · 6 reporting periods · 2 of 10 challenging
DHR company page →

Calendar 2026 Q1

from a readiness standpoint, could you do something in any segment as we sit here today

M&ACapital AllocationTranscript · FY2026 Q1 →
Show response

Blair confirmed M&A readiness across all 3 segments with no segment-level constraints from the pending Masimo integration. Signaled both financial capacity and management bandwidth are available.

What gets you to the high end of guidance for the year? Is it really just what you described there

Guidance ReliabilityRevenue GrowthTranscript · FY2026 Q1 →
Show response

Gugino outlined 3 requirements for high-end attainment: further Life Sciences end market improvement, bioprocessing acceleration beyond high single digits in consumables plus equipment growth, and above-normal Q4 respiratory season back to ~$1.8B endemic rate.

Calendar 2025 Q4

Can you just describe the M&A environment and your readiness and your priorities to potentially get a little more aggressive

M&ACapital AllocationTranscript · FY2025 Q4 →
Show response

Rainer confirmed improving M&A environment with better valuations and moderating interest rates. Balance sheet is prime for action. Maintaining disciplined framework but bias toward M&A remains strong.

it's a smidge surprising you didn't guide for maybe a little more growth at that line. Was there any pull forward of demand

ChallengingCapex InvestmentGuidance ReliabilityTranscript · FY2025 Q4 →
Show response

Matt emphasized prudence, one quarter of growth is not a trend. Guiding flat for equipment as starting point. Will adjust as more data points confirm the trajectory.

Calendar 2025 Q3

Have you seen any change in activity over the last few weeks or even just -- even in the tone of discussions

MacroeconomicDemandTranscript · FY2025 Q3 →
Show response

Rainer confirmed improving tone in pharma discussions but not yet reflected in guidance, needs demonstrated order patterns before calling the trend. More confidence on tariffs and MFN becoming plannable.

is there an argument that even though you talked about 100 basis points of margin expansion potential next year

MarginGuidance ReliabilityTranscript · FY2025 Q3 →
Show response

Matt confirmed north of 100bps expansion is the right frame. $250M net savings drives $0.30 EPS tailwind. Company wants room to continue investing while delivering high-single-digit EPS growth.

Calendar 2025 Q2

you had previously told us to expect high single-digit bioprocessing revenue growth for the year. Is that still the case

Revenue GrowthPricingTranscript · FY2025 Q2 →
Show response

Confirmed high-single-digit guide. H1 pricing 1.5-2%, similar or slightly better in H2. D&M slightly lower offset by better bioprocessing; full segment guide maintained.

Calendar 2025 Q1

I just want to make sure this is a continuation of trend and not really anything new in terms of a further deterioration

M&AGuidance ReliabilityTranscript · FY2025 Q1 →
Show response

Aldevron tracking as anticipated, expects improvement in H2 as comps ease. On EPS, $7.60-$7.75 includes cushion from remaining ~$100M of cost savings not yet in guide, balancing macro uncertainty.

Calendar 2024 Q4

So it's hard for a stock to work, when the estimates keep moving in the wrong direction

ChallengingGuidance ReliabilityTranscript · FY2024 Q4 →
Show response

Matt acknowledged EPS trajectory concern but defended bottom-up approach. Noted external headwinds were worked through and margin profile remained strong despite two down years.

this implies kind of what's embedded into your guidance, is an implied 5% core and normalized diagnostic growth rate

Revenue GrowthGuidance ReliabilityTranscript · FY2024 Q4 →
Show response

Matt confirmed diagnostics ex-China is mid-to-high single-digits, in line with long-term aspiration. Headwinds are China VBP and respiratory normalization.

AAgilent Technologies9 questions · 5 reporting periods · 2 of 9 challenging
A company page →

Calendar 2026 Q1

how would you describe demand month-by-month going back to, say, November and December and through the beginning of the calendar year?

DemandMacroeconomicTranscript · FY2026 Q1 →
Show response

Padraig described steady to growing funnels. Reasonable budget flush in December, some intra-quarter disruption in Europe and weather in January. No deterioration in CapEx conditions. MFN deals reducing tariff uncertainty for pharma. Comprehensive.

how would you describe the environment, your readiness and your appetite to do a multibillion dollar deal?

M&ACapital AllocationTranscript · FY2026 Q1 →
Show response

Adam was deliberate: no arbitrary size filter but very high bar for transformative deals. Organic business is strong enough without transformation. Focused on strategic fit, right to win, integrability, and right price. Nice opportunities being evaluated.

Calendar 2025 Q4

I think you guys were down 10% constant currency in the quarter, if I updated the model right. You know, I think this is a little bit surprising given seasonality

ChallengingMacroeconomicRegulation PolicyTranscript · FY2025 Q4 →
Show response

Padraig attributed to US federal spending reductions. Americas instruments down mid-twenties, services/consumables resilient at low single digits. Ex US stable sequentially. No material government shutdown impact. Continued FY2026 softness expected. Direct.

How big is this business? I'm thinking it's probably around $100 million coming out of last year.

DemandRevenue GrowthTranscript · FY2025 Q4 →
Show response

Padraig quantified GLP-1 at ~$130M for FY2025, split evenly BioVectra/analytical lab. Q4 revenue ~$40M (60% BioVectra, 40% analytical). Analytical lab grew 40% on Alturo columns and Infinity 3. India as key generics opportunity. Very detailed.

Calendar 2025 Q3

How do you balance momentum and strength with the goal of maybe skewing the error bars around your guidance targets to the upside?

Guidance ReliabilityTranscript · FY2025 Q3 →
Show response

Padraig stated very good Q4 visibility on orders, revenue, and margins. Positive momentum expected to continue into FY2026 but formal guidance deferred to next quarter. Direct.

how would you describe organizational readiness for something bigger given how how how many changes have occurred in leadership over the past year?

M&ACapital AllocationTranscript · FY2025 Q3 →
Show response

Padraig emphasized Ignite as integration capability, M&A expected to be more meaningful going forward. Disciplined approach aligned to strategy pillars. Small list of high-quality targets. Also investing heavily in digital/CRM internally.

Calendar 2025 Q1

it would be interesting to hear if there's anything, interesting that occurred in terms of a particular rebound in specific instrument categories, specific geographies

DemandRegulation PolicyTranscript · FY2025 Q1 →
Show response

Padraig confirmed solid December driven by Infinity III, PFAS, GLP-1. January steady with only academia softness. PFAS business unchanged. Thorough.

Calendar 2024 Q4

is it fair to say that the error bar around your assumptions are wider than normal heading into a new fiscal year and your intent across the board was to make assumptions

ChallengingGuidance ReliabilityMacroeconomicTranscript · FY2024 Q4 →
Show response

Padraig openly confirmed wider error bars and intentional conservatism across China, LC replacement, and policy uncertainty. Transparent.

I believe in your prepared remarks, you indicated that small molecule was up low single digits while biopharma was down mid-singles. If I have that right, is that comp effect

DemandCompetitive DynamicsTranscript · FY2024 Q4 →
Show response

Bob explained NASD impact on biopharma numbers, volume dynamics in small molecule, and why it was first to recover. Detailed and analytical.

ILMNIllumina, Inc.6 questions · 6 reporting periods · 1 of 6 challenging
ILMN company page →

Calendar 2026 Q1

How should we think about the margin progression throughout the year?

MarginCost PressureTranscript · FY2026 Q1 →
Show response

Ankur (answering Madeleine on for Doug) cited higher instrument mix, inflation and a full quarter of SomaLogic pressuring Q2, with mitigation benefits visible in H2.

Calendar 2025 Q4

Does guidance embed an assumption that you essentially end the year at 26% to 27% operating margin?

MarginCapital AllocationTranscript · FY2025 Q4 →
Show response

Jacob reaffirmed the 2027 26% margin target and to get as close as possible including SomaLogic; Ankur confirmed the Q4 exit rate typically runs above the full-year 24.5%.

Calendar 2025 Q3

mathematically, it gets me to low single-digit revenue growth, at least as a starting point for next year.

Revenue GrowthGuidance ReliabilityTranscript · FY2025 Q3 →
Show response

Jacob broadly endorsed the clinical-led framework without guiding, excluding China; Ankur pointed to further margin expansion from cost actions and operating leverage.

Calendar 2025 Q2

your guidance implies the company will generate about 2 points of revenue growth in the fourth quarter, excluding China

Revenue GrowthGuidance ReliabilityTranscript · FY2025 Q2 →
Show response

Jacob declined to give 2026 guidance but confirmed the X transition and clinical as the main drivers, with multiomics adding growth from 2026-2027.

Calendar 2025 Q1

outside of China, what was your total clinical revenue growth and what was your total research growth

DemandRevenue GrowthTranscript · FY2025 Q1 →
Show response

Ankur quantified clinical consumables up mid-single digits and research down mid-to-high single digits, guiding research to a ~15% decline for the rest of the year.

Calendar 2024 Q4

I'm wondering if you would at least be willing to talk about the levers you have identified

ChallengingMarginCapital AllocationTranscript · FY2024 Q4 →
Show response

Ankur pointed to 170bps of margin expansion in the base case plus additional earnings-growth opportunities, without ring-fencing China.

MTDMettler Toledo6 questions · 4 reporting periods · 0 of 6 challenging
MTD company page →

Calendar 2026 Q1

Could you elaborate a bit more on the grant proceeds recognized in the quarter?

Geographic ExpansionCapex InvestmentTranscript · FY2026 Q1 →
Show response

Shawn described a local Shanghai government grant encouraging capacity and research, split between CapEx and OpEx, excluded from free cash flow.

any product categories or geographies that got, you know, notably better or worse in April versus March

DemandMacroeconomicTranscript · FY2026 Q1 →
Show response

Shawn declined month-level detail, pointing back to the Q2 and full-year guidance by product area and region.

Calendar 2025 Q4

What would you call out as driving the underlying improvement? So not just in process analytics and bioprocessing, but more broadly

Revenue GrowthDemandTranscript · FY2025 Q4 →
Show response

Patrick confirmed some budget flush activity with better momentum late in Q4. Beyond bioprocessing, LabX software solution driving automation of broader workflows in R&D and QA/QC labs. Digital capabilities and connectivity across lab portfolio creating competitive differentiation.

Calendar 2025 Q3

how much of this was driven by PA process analytics versus traditional lab equipment

Revenue GrowthDemandTranscript · FY2025 Q3 →
Show response

Shawn confirmed PA/bioprocessing was lab highlight plus power grid investments for data centers. Analytical instruments and weighing also grew well. Liquid handling soft spot. On industrial, transportation/logistics dynamic dimensioning contributed, timing skewed Q3 vs Q4. Q4 core industrial guided low single digit.

Calendar 2025 Q2

You talked in your prepared remarks about strong demand for automation. I'm just wondering if you could tell us a little bit more about that

Capex InvestmentInnovation & R&DTranscript · FY2025 Q2 →
Show response

Patrick highlighted automation solution providers calling on MTD innovations across pharma, general manufacturing. Good momentum in US, China, and Asia Pacific.

if Europe kind of returns to normal and starts to get a little bit better, and by normal, I mean, what you've seen in the last few quarters, if China starts to get a smidge better

DemandGeographic ExpansionTranscript · FY2025 Q2 →
Show response

Shawn acknowledged Europe upside potential offset by tougher Q4 comps. China remains wildcard, bouncing along bottom. Well positioned with China-for-China business but cautious H2 guide.

RVTYRevvity5 questions · 3 reporting periods · 0 of 5 challenging
RVTY company page →

Calendar 2025 Q3

I believe China Diagnostics is down to about 5% of total sales exiting Q3. I want to make sure that's right

Regulation PolicyRevenue GrowthTranscript · FY2025 Q3 →
Show response

Max corrected China DX to ~6% of revenue. Expects DRG headwinds to continue until Q2 2026 anniversary, then low-single-digit growth per LRP. IDx ex-China up high single digits.

Calendar 2025 Q2

When would you expect this to annualize? Do you have visibility on whether or not this is the last cut?

Regulation PolicyRevenue GrowthTranscript · FY2025 Q2 →
Show response

Prahlad noted annualization expected around late April 2026. IDx China now less than 6% of revenue, likely less than 5% in FY26.

it looks like you're assuming similar revenue pacing to last year. I just want to make sure that's right

Revenue GrowthRegulation PolicyTranscript · FY2025 Q2 →
Show response

Max confirmed normal Q3-to-Q4 seasonality with Genomics England ramp and larger Signals quarter in Q4.

Calendar 2024 Q4

What does your guidance assume for core growth within the region this year? How are you thinking about stimulus within the context of guidance?

Geographic ExpansionDemandTranscript · FY2024 Q4 →
Show response

Max confirmed China assumed in line with company at 3-5%, LS at higher end, Diagnostics at lower. Stimulus modest.

what are the major areas where you would say things are back to normal, where are the things were -- or areas where you would say we're getting close?

DemandRevenue GrowthTranscript · FY2024 Q4 →
Show response

Prahlad provided clear breakdown: Diagnostics and software at normal, reagents getting closer, instruments still lagging.

WSTWest Pharmaceutical Services5 questions · 5 reporting periods · 1 of 5 challenging
WST company page →

Calendar 2025 Q4

Are you comfortable saying, as built, even in a conservative scenario for GLP-1s, that your revenue can grow at least mid to high single digits over the next several years

Guidance ReliabilityRevenue GrowthTranscript · FY2025 Q4 →
Show response

Bob confirmed comfort with mid-to-high single digit revenue growth over the next several years, combining conservative GLP-1 assumptions with non-GLP-1 HVP recovery and Annex-1 tailwinds.

Calendar 2025 Q3

I want to confirm that you essentially bumped up guidance by the magnitude of the revenue beat

ChallengingGuidance ReliabilityCompetitive DynamicsTranscript · FY2025 Q3 →
Show response

Bob confirmed no material pull-forward in Q3, noting Q4 is actually an acceleration on a 2-year stack. On visibility, emphasized improving transparency, deeper segment accountability, and closer customer engagement as reducing risk profile.

Calendar 2025 Q2

as currently built and with no material changes in policy dynamics are there any things you would want us to contemplate as we update our out-year model

Guidance ReliabilityTrade TariffsTranscript · FY2025 Q2 →
Show response

Bernard confirmed tariff guidance based on known rates at time of guidance, with Japan change not fully contemplated but immaterial. Eric expressed strong confidence in HVP momentum building but declined to comment specifically on 2026.

Calendar 2025 Q1

could you share anything in terms of what are the what's the status of discussions pursuant to getting the price

PricingTrade TariffsTranscript · FY2025 Q1 →
Show response

Bernard confirmed no SmartDose pricing or tariff pass-through embedded in guidance; both represent potential upside if materialized.

Calendar 2024 Q4

GLP-1 is a percentage of sales are about 10%. I just want to make sure that's right

DemandRevenue GrowthTranscript · FY2024 Q4 →
Show response

Eric confirmed GLP-1 is approximately 10% of total revenue, split roughly 40% of contract manufacturing and mid-single digits of proprietary.

Show 4 more companies
WATWaters Corporation4 questions · 3 reporting periods · 3 of 4 challenging
WAT company page →

Calendar 2026 Q1

I'm just wondering if there's been any notable competitive responses worth calling out

Competitive DynamicsM&ATranscript · FY2026 Q1 →
Show response

Doug asked about competitive response to Waters' new discipline and PE-owned competitor dynamics. Udit emphasized leading brands across all four divisions and expected rational pricing from PE players. Confident but no specific competitive data points.

Calendar 2025 Q4

your initial year 1 guidance assumes you cut 5% to 6% of the acquired businesses OpEx, assuming I have that math right

ChallengingM&AMarginTranscript · FY2025 Q4 →
Show response

CFO noted underwriting assumed 4-4.5% vs 6% typical for deals this size and 8% achieved at MilliporeSigma. Kept room for integration skeletons while confirming on track for deal announcement commitments.

Calendar 2025 Q3

you beat the quarter from a revenue standpoint, but you increased full year guidance by less than the magnitude of the beat

ChallengingGuidance ReliabilityMarginTranscript · FY2025 Q3 →
Show response

CFO noted quarterly timing of bonus true-ups, commissions and discrete tax items but stressed full-year delivery is on track.

The downside to that is the comps are difficult. I just want to make sure, as we sit here today, are you still comfortable with us modeling something like 6% to 8% core growth

ChallengingGuidance ReliabilityDemandTranscript · FY2025 Q3 →
Show response

Management described excellent 2026 setup with replacement cycle mid-innings, multiple new product catalysts and improving end markets.

TMOThermo Fisher Scientific3 questions · 2 reporting periods · 1 of 3 challenging
TMO company page →

Calendar 2025 Q1

you have to at least contemplate a scenario where the market growth rate is structurally lower

ChallengingMacroeconomicCompetitive DynamicsGuidance ReliabilityTranscript · FY2025 Q1 →
Show response

Casper acknowledged GDP growth is a factor in long-term market growth but emphasized industry resilience and committed to transparent communication if views change.

I'm curious what you're seeing in terms of movement towards reshoring in the US

Capex InvestmentGeographic ExpansionDemandTranscript · FY2025 Q1 →
Show response

Casper said new facility announcements drive meaningful revenue across bioproduction and bioscience, but timing is mainly 2026 and beyond.

Calendar 2024 Q4

are you expecting to exit 2025 back in your targeted 7% to 9% organic growth range

Revenue GrowthMarginGuidance ReliabilityTranscript · FY2024 Q4 →
Show response

Casper indicated the exit rate would be strong mid-single digits (not yet 7-9% due to pandemic headwind) and attributed margin expansion to PPI execution, not mix.

HOLXHologic2 questions · 2 reporting periods · 0 of 2 challenging
HOLX company page →

Calendar 2025 Q2

Are there any dynamics we should be contemplating in our models, either tailwinds or headwinds that could move you off trend towards continued progress

Guidance ReliabilityRevenue GrowthTranscript · FY2025 Q3 →
Show response

Karleen flagged Fluoroscan discontinuation and continuing China/HIV headwinds into FY2026 H1 as key modeling considerations. Also confirmed mid-single-digit organic growth expectation for FY2026.

Calendar 2024 Q4

how much of the change in your assumption that you've embedded into guidance for Breast Health as a function of market conditions

Show response

Steve weighted market conditions as bigger driver than pre-launch stalling. Karleen outlined M&A criteria: revenue accretive, at or above corporate gross margins, double-digit ROIC within reasonable timeframe.

TEMTempus AI, Inc.2 questions · 2 reporting periods · 0 of 2 challenging
TEM company page →

Calendar 2025 Q2

Is there a good rule of thumb on just how you're going to think about partnering versus organic?

M&ACapital AllocationTranscript · FY2025 Q2 →
Show response

Eric said any deal must be synergistic and not derail the path to adjusted EBITDA positive.

Calendar 2024 Q4

what's the appetite for more M&A based on your balance sheet situation in the current market environment?

M&ACapital AllocationTranscript · FY2024 Q4 →
Show response

Eric said nothing big is on the horizon; only smaller data/AI deals are likely.

Challenge rate by company

Every company this analyst questioned, most questions first. A company-level rate is shown from 3 questions; below that it is withheld.

CompanyQuestionsChallenge rate
DHR Danaher Corporation1020%2 of 10 questions
A Agilent Technologies922%2 of 9 questions
ILMN Illumina, Inc.617%1 of 6 questions
MTD Mettler Toledo60%none of 6 questions
RVTY Revvity50%none of 5 questions
WST West Pharmaceutical Services520%1 of 5 questions
WAT Waters Corporation475%3 of 4 questions
TMO Thermo Fisher Scientific333%1 of 3 questions
HOLX Hologic2—Rate withheld: fewer than 3 questions
TEM Tempus AI, Inc.2—Rate withheld: fewer than 3 questions
  • DHR
    Danaher Corporation · 10 questions
    20%2 of 10 questions
  • A
    Agilent Technologies · 9 questions
    22%2 of 9 questions
  • ILMN
    Illumina, Inc. · 6 questions
    17%1 of 6 questions
  • MTD
    Mettler Toledo · 6 questions
    0%none of 6 questions
  • RVTY
    Revvity · 5 questions
    0%none of 5 questions
  • WST
    West Pharmaceutical Services · 5 questions
    20%1 of 5 questions
  • WAT
    Waters Corporation · 4 questions
    75%3 of 4 questions
  • TMO
    Thermo Fisher Scientific · 3 questions
    33%1 of 3 questions
  • HOLX
    Hologic · 2 questions
    —rate withheld: under 3 questions
  • TEM
    Tempus AI, Inc. · 2 questions
    —rate withheld: under 3 questions

Activity by reporting period

Questions recorded for each calendar quarter that companies’ reporting periods map to (not the call date), with the challenge rate for that period. Periods inside the range with no questions are shown as “No questions recorded”.

Questions by calendar reporting period
Calendar periodQuestionsChallenge rateCompanies
2024 Q41127%3 of 11 questions8
2025 Q1617%1 of 6 questions5
2025 Q290%none of 9 questions7
2025 Q31030%3 of 10 questions7
2025 Q4838%3 of 8 questions6
2026 Q180%none of 8 questions5
  1. 2024 Q411 questions · challenge rate 27% (3 of 11 questions) · 8 companies
  2. 2025 Q16 questions · challenge rate 17% (1 of 6 questions) · 5 companies
  3. 2025 Q29 questions · challenge rate 0% (none of 9 questions) · 7 companies
  4. 2025 Q310 questions · challenge rate 30% (3 of 10 questions) · 7 companies
  5. 2025 Q48 questions · challenge rate 38% (3 of 8 questions) · 6 companies
  6. 2026 Q18 questions · challenge rate 0% (none of 8 questions) · 5 companies

Topics

Topics tagged on this analyst’s questions.

  • Guidance Reliability18
  • Revenue Growth17
  • Demand16
  • M&A10
  • Capital Allocation8
  • Margin7
  • Macroeconomic6
  • Regulation Policy5
  • Geographic Expansion4
  • Capex Investment4
Show all 15 topics
  • Competitive Dynamics4
  • Pricing2
  • Trade Tariffs2
  • Cost Pressure1
  • Innovation & R&D1