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Have you seen any seasonality during the fourth quarter, potentially patients who pushed the injection to the next quarter because of the holidays and whether this can be a tailwind to 2026
We have seen some commercial payers requiring stabilizer use prior to AMVUTTRA treatment in cardiomyopathy
whether you see the majority of the early AMVUTTRA uptake coming from switch patients or new patients
what are your thoughts around step edits for commercial insured patients who represent about 20%