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Analyst
Matt Larew
Period: Reporting periods mapped to calendar 2024 Q3 – 2026 Q2 (8 quarters).
- Questions
- 28on tracked calls
- Challenge rate
- 14%4 of 28 questions
- Companies
- 4questioned at least once
- Reporting periods
- 8with questions
These figures cover the whole profile: every tracked question, all reporting periods.
How to read these numbers
Challenge rate is the share of questions that pushed back, pressed for specifics or questioned management’s assumptions. It describes how questions were asked on the calls tracked here; it does not measure whether any view turned out to be right.
Rounding. Rates are rounded to whole percentages, so a small share can show as 0% even when some questions were challenging. The count beside each rate is exact; “none of N questions” means no question was challenging.
No questions recorded. “—” means there is nothing to calculate: no questions were recorded for that period on the calls tracked here. It does not mean there was no activity.
Fewer than 3 questions. A company-level rate is withheld when fewer than 3 questions were recorded for that company; the questions are still counted everywhere else.
Small samples. Profiles with fewer than 10 questions are marked Limited sample.
Reporting periods. Questions are grouped by the calendar quarter each company’s fiscal reporting period maps to, not by the date of the call. Periods without a calendar mapping are listed separately under their fiscal label.
Questions asked
Grouped by company, most questions first. Open a company to read its questions, newest reporting period first.
Showing 28 of 28 questions from 4 companies
TECHBio-Techne14 questions · 7 reporting periods · 2 of 14 challenging
Calendar 2026 Q1
would just be curious if you're thinking that sort of the mid-single-digit range by the end of the year, again, kind of consistent with improvement in others are citing
Show response
Jim expressed encouragement about FY2027 with company-specific headwinds behind them, definite academic stabilization, and strong pharma. Agreed with peers expecting uptick in second half of calendar 2026 pending biotech recovery. Won't give soft FY2027 guidance until next quarter.
I would be curious what you saw from sort of an intra-quarter trend perspective and if you've seen any improvement sort of from January through to March and then now into April
Show response
Kim acknowledged biotech surprised to the downside, stepped down from mid-single digit declines to high single digit despite funding improvements. Early-stage biotech funding was actually down while late-stage was up. Conversations are improving but cannot assume clear stabilization.
Calendar 2025 Q4
So Jim, just following up on growth cadence. So 1% ex items in fiscal Q1, then 3%.
Show response
Jim confirmed low single digit full year view unchanged, requiring mid-single-digit Q4. Kim clarified that excluding the two GMP headwind customers, the underlying growth trajectory is in the ballpark of mid-single digits.
Jim, maybe just give a sense for why on a sequential basis, gross margins were down and how those should trend for the balance of the year
Show response
Jim cited unfavorable mix across reagents vs instruments, spatial underperforming higher-margin diagnostics, and lower-margin OEM customer orders. Expects overall mix to gradually improve in Q3 and Q4.
Calendar 2025 Q3
Historically, you've thought about kind of a 2- to 3-quarter lag there. I'm curious given how long we've sort of been in the doldrums
Show response
Kim noted that unlike previous cycles where funded companies needed to build infrastructure first, current biotech recipients already have facilities in place. This suggests funding could translate to Bio-Techne revenue faster than the historical 2-3 quarter lag.
can you maybe just speak to ex-CTX, how you see the balance of the year unfolding in light of the macro dynamics you referenced?
Show response
Jim confirmed underlying business ex-2 customers grew 1% in Q1, expects to accelerate to 3% in Q2, with further improvement in H2 from lapping administration policy impacts and stronger diagnostics ordering patterns.
Calendar 2025 Q2
How are you thinking about M&A, be it by segment, be it by stage of company or relative profitability and potential?
Show response
Kim outlined M&A focus on three areas: core reagent additions for global distribution, cell therapy workflow capabilities, and ProteinSimple instrumentation adjacencies. Described maintaining a precise target list that they are actively nurturing.
What did you learn about budget unlock and what will really kind of catalyze spend from those different sets of uncertainties
Show response
Jim shared that academic customers are overreacting relative to actual NIH exposure, cutting spending 10-15% across the board preemptively. Believes current behavior is worse than any actual funding outcome, making resolution an upside catalyst.
Calendar 2025 Q1
at 8.5% street organic growth for next year and maybe the way you're guiding us for fiscal 2025, at least more reasonable starting point than the Street's at today?
Show response
Jim declined to validate or reject 8.5% consensus but framed current headwinds as temporary, noting trajectory was strong before policy shocks. Expressed hope for more clarity in three months but did not provide a specific FY2026 starting point.
can you just speak to sort of the tension between ongoing cost containment and investments and where you're seeing additional opportunities to drive leverage?
Show response
Jim credited multi-year structural streamlining and diligent discretionary cost control, especially during recent uncertainty. Kim added efficiency gains from management process improvements, ERP modernization, acquisition integration, and operational optimization.
Calendar 2024 Q4
Wondering if you could break that out. Is it still sounds like it's mainly large pharma most of the recovery is
Show response
Kim noted biotech recovery in line with expectations (~30% of revenue), but large pharma improvement was better than expected. Jim added smaller biotechs gradually progressing while large pharma started recovering earlier than the April-May expectation.
what is your assessment And then, you know, what's key to of the competitive landscape at this point
Show response
Kim noted competitive M&A activity as positive validation for spatial biology market. Corrected that RNAscope multiomics launched last quarter. Profitability to improve via instrument uptake and consumable pull-through.
Calendar 2024 Q3
The extent you have visibility to this is sort of the pickup in work that you maybe assess was paused or on hold or delayed and now is returning, or is this related to, you know, new project work
Show response
Kim confirmed both existing customers progressing through clinical phases with larger orders and new customers being added to the funnel, with broad activity improvement.
That space obviously remains competitive with new entrants looming, and you are clearly investing back in the future there
Show response
Kim cited G-Rex's scalability, cost, flexibility and performance advantages and emphasized synergies with GMP proteins. Grant program seeds customers early in preclinical development.
WSTWest Pharmaceutical Services8 questions · 6 reporting periods · 1 of 8 challenging
Calendar 2026 Q2
what's most interesting to you on the delivery device side, maybe not thinking about the next 3 months
Show response
Eric highlighted SelfDose, Crystal Zenith for high-end biologics, and administration systems, with an attractive margin profile after SmartDose 3.5 exits.
Calendar 2025 Q4
Maybe give us an update on where you are excited about the device opportunity going forward
Show response
Eric positioned Synchrony prefillable syringe as an extension of the HVP spectrum, not comparable to SmartDose. Economics are very attractive. Already received orders since Italian launch. Long-term pipeline play similar to NovaPure adoption curve.
Calendar 2025 Q3
how are you thinking about the levels of CapEx needed to support growth
Show response
Eric confirmed CapEx returning to 6-8% of sales, focused on HVP centers of excellence campus expansion rather than greenfield. Tech transfers take 12-18 months. Elastomer components less than 1% of drug COGS. Bob noted no change in customer buying behavior from MFN headlines.
Calendar 2025 Q2
you've been working to ramp up labor to address that. You raised the guide back to mid- to high single digits, but it sounds like those labor constraints are still in place
Show response
Eric confirmed he visited the constrained European facility personally, team executing well on ramp-up plans. New team members take several weeks to get up to speed. Opportunity to continue accelerating with confidence in delivering mid-to-high single digit HVP growth.
Calendar 2025 Q1
whether you still feel confident in the longer-term growth plan you've outlined
Show response
Eric said injectable delivery will remain the majority of GLP-1 market. Models already incorporate shared oral/injectable assumptions, and HVP assets are fungible from COVID capacity.
you have enough pieces in place that you made enough progress that the time line you've cited that you feel confident
Show response
Eric confirmed automation timeline on schedule for end-of-year validation and commercialization, with earlier delays now resolved.
Calendar 2024 Q4
Could you frame what year like, how that participation rate and duration of contract would compare to your prior
Show response
Eric explained the contract secures the existing full-share position for a very long duration, calling it a natural progression of the relationship.
is there an existential question as to whether that should be a core competency of the company long term
Show response
Eric acknowledged strategic review of SmartDose specifically while emphasizing the broader delivery device portfolio remains valuable.
TMOThermo Fisher Scientific5 questions · 3 reporting periods · 0 of 5 challenging
Calendar 2026 Q2
The biggest delta versus our model was on Analytical Instruments and acknowledging that the comparable was easy that certainly stood out.
Show response
Marc credited innovation and product launches, including two mass spectrometers and electron microscopy strength.
Calendar 2026 Q1
how does -- how customers might shift the way they are using your instruments affect the way that you're thinking about developing them?
Show response
Marc described the trend toward automated, data-connected labs for biology model building, noting instrument R&D roadmaps focus on better connectivity for these scaled facilities.
Would just be curious your level of confidence that, that will remain a tailwind? And what sort of the activity level has been like for Thermo?
Show response
Marc confirmed reshoring contracts signed in CDMO, brownfield bioproduction wins secured, with revenue largely a 2027-2028 tailwind. President Trump visited their Cincinnati drug product site.
Calendar 2025 Q4
how some of these ecosystems changes are affecting customer preferences for outsourcing in general
Show response
Casper said Accelerator Drug Development is driving meaningful authorization wins for CRO and new pharma services contracts, with OpenAI collaboration focused on further shaving time and cost.
what you've seen about their wet lab activity, their demand for instruments
Show response
Casper said AI reduces wasted experiments but increases confidence-driven wet lab work, and TMO is optimistic about the intersection of AI and wet lab demand.
WATWaters Corporation1 question · 1 reporting period · 1 of 1 challenging
Calendar 2025 Q4
might be suggestive of a business in need of commercial investment to improve execution. How do you think about the level of investment needed for the business long term
Show response
Management described deploying central commercial excellence teams for pricing discipline, launch readiness and segmentation, replicating the Waters playbook with specialists embedded across new divisions.
Challenge rate by company
Every company this analyst questioned, most questions first. A company-level rate is shown from 3 questions; below that it is withheld.
| Company | Questions | Challenge rate |
|---|---|---|
| TECH Bio-Techne | 14 | 14%2 of 14 questions |
| WST West Pharmaceutical Services | 8 | 13%1 of 8 questions |
| TMO Thermo Fisher Scientific | 5 | 0%none of 5 questions |
| WAT Waters Corporation | 1 | —Rate withheld: fewer than 3 questions |
Activity by reporting period
Questions recorded for each calendar quarter that companies’ reporting periods map to (not the call date), with the challenge rate for that period. Periods inside the range with no questions are shown as “No questions recorded”.
| Calendar period | Questions | Challenge rate | Companies |
|---|---|---|---|
| 2024 Q3 | 2 | 50%1 of 2 questions | 1 |
| 2024 Q4 | 4 | 25%1 of 4 questions | 2 |
| 2025 Q1 | 4 | 25%1 of 4 questions | 2 |
| 2025 Q2 | 3 | 0%none of 3 questions | 2 |
| 2025 Q3 | 3 | 0%none of 3 questions | 2 |
| 2025 Q4 | 6 | 17%1 of 6 questions | 4 |
| 2026 Q1 | 4 | 0%none of 4 questions | 2 |
| 2026 Q2 | 2 | 0%none of 2 questions | 2 |
- 2024 Q32 questions · challenge rate 50% (1 of 2 questions) · 1 company
- 2024 Q44 questions · challenge rate 25% (1 of 4 questions) · 2 companies
- 2025 Q14 questions · challenge rate 25% (1 of 4 questions) · 2 companies
- 2025 Q23 questions · challenge rate 0% (none of 3 questions) · 2 companies
- 2025 Q33 questions · challenge rate 0% (none of 3 questions) · 2 companies
- 2025 Q46 questions · challenge rate 17% (1 of 6 questions) · 4 companies
- 2026 Q14 questions · challenge rate 0% (none of 4 questions) · 2 companies
- 2026 Q22 questions · challenge rate 0% (none of 2 questions) · 2 companies
Topics
Topics tagged on this analyst’s questions.
- Demand10
- Revenue Growth7
- Innovation & R&D7
- Margin5
- Competitive Dynamics5
- Guidance Reliability4
- Macroeconomic3
- Product Launch3
- Cloud & AI3
- Cost Pressure2
Show all 16 topics
- Supply Chain2
- M&A2
- Capital Allocation2
- Capex Investment2
- Regulation Policy1
- Trade Tariffs1